Category: Synthesizing Evidence

Appraising Evidence, Evidence Based Practice, Home, Synthesizing Evidence

Is onabotulinumtoxinA effective in reducing lower limb spasticity in children with cerebral palsy?

Cerebral palsy (CP) is a neurodevelopmental disorder that affects motor function and is often associated with spasticity, which can result in pain and reduced quality of life. OnabotulinumtoxinA, commonly known as Botox, has been used as a treatment for spasticity in CP. This article reports on a phase 3, multinational, randomized, double-blind, placebo-controlled trial that evaluated the safety and efficacy of onabotulinumtoxinA for lower limb … Continue reading Is onabotulinumtoxinA effective in reducing lower limb spasticity in children with cerebral palsy?

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Appraising Evidence, Evidence Based Practice, Home, Synthesizing Evidence

How Do Dutch Multidisciplinary Guidelines Help Manage Low Back Pain and Lumbosacral Radicular Syndrome?

Low back pain (LBP) is a common health issue that affects individuals worldwide, and it is a major cause of disability, morbidity, and lost productivity in the workplace. To address this issue, the first Dutch multidisciplinary practice guideline for occupational health professionals was developed to enhance work participation and prevent LBP and lumbosacral radicular syndrome (LRS). The guideline was developed by a multidisciplinary working group … Continue reading How Do Dutch Multidisciplinary Guidelines Help Manage Low Back Pain and Lumbosacral Radicular Syndrome?

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